Inspecting someone's privates or brain wiring is so 20th Century. The universally accepted test of gender is to spin people around three times, put them in a car in a strange place and see if they'll ask for directions.
For the record, even if you don't think someone who's bio. a woman but mentally a man (or visca versa), I'd really hope you'd put your opinions aside and call them what they wished to be called,
Yes there are anatomical differences, such as the number of connectors from the left side to the right side of the brain and surely the use of different brain departments. However brains do not have gonads...
One doesn't hook up a baby to a brain monitor and analyze the usage of different brain areas to determine if the baby is male or female. This is absurd.
Think of it this way: If you call any limbless reptile a snake, 99% of the time you'll be correct. And that quick, approximate definition is good enough for most people's needs. But that's not *actually* what defines a snake, and if you want to *actually* know for sure, you need to be more in-depth.
The same thing here - 99% of the time (or more) the external matches the brain, so it's a useful first approximation, especially considering the cost for running a single fMRI scan. But every so other, you get the analog of a legless lizard - something that looks like one thing, but is something else.
Mokele
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But you herp groupies . . . herpies . . . never mind . . . are overlooking the key question; what does that legless lizard or that legged snake want to be called?

You know... I just had an idea. If you really believe you're a man, and you call yourself a man, and you live as a man....
Why would you allow yourself to become pregnant in the first place, even if you're pre-op, much less have a baby? That's not living as a man, that's living as a woman. Men can't get pregnant, so if you think and say you're a "real" man, you shouldn't allow yourself to become pregnant. Ever. If you do, it really makes you look like a hypocrite. You can't be a real man only when it's convenient for you. You want a baby? Fine. Let someone else be the sperm donor for your partner's egg. Maybe he's gay? Then there's no egg to use if he's seriously a man. Adopt. Hell, adopt regardless.
No one is more liberal than I am on social issues, but one thing I don't like is hypocrisy. He's a hypocrite. I consider GLBT people like brothers and sisters, but he's a hypocritic brother. You can't have your cake and eat it to and expect too be taken seriously. If you could, I'd trade not having my hair fall out for periods any day of the week.... I mean five days of the month.
.That's like if I put a Escillade chasis on my Explorer and then tell everyone that I own a Cadillac.
or maybe not.
You raise a very good point Clint, one that I have been chewing on.